Transcriptional activators and activation mechanisms

Jun Ma. Transcriptional activators and activation mechanisms[J]. Protein&Cell, 2011, 2(11): 879-888. doi: 10.1007/s13238-011-1101-7

Citation:

Jun Ma. Transcriptional activators and activation mechanisms[J]. Protein&Cell, 2011, 2(11): 879-888. doi: 10.1007/s13238-011-1101-7

Citation:

Jun Ma. Transcriptional activators and activation mechanisms[J]. Protein&Cell, 2011, 2(11): 879-888. doi: 10.1007/s13238-011-1101-7

Abstract

Transcriptional activators are required to turn on the expression of genes in a eukaryotic cell. Activators bound to the enhancer can facilitate either the recruitment of RNA polymerase Ⅱ to the promoter or its elongation. This article examines a few selected issues in understanding activator functions and activation mechanisms.

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